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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aabbe427198a1f54bec8fc1efc975611f9bdca1b74970a43726294251e830a66' 
  AND token = 'UDii2TQUaE7tih1/21uL3wB132KDAXOv2OBd12sLTac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}