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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf87dc12af86b85108801eb2325ecfb39200b76f29d9699f3d7f9ff9ac1a663' 
  AND token = 'gI7FZ4S99kSwR6p7QcAdkoCawuhJIrV/bWUZbYm1p5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}