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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1673f9a26e0489ea907ce0fcf64ba49ea7ac6d8e1a86c721899799bfda6015' 
  AND token = 'kjecFhpYvjOAmq1eum4xLOauFb0NZ8ZJu5QOU8gAVoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}