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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a6e41f19ff5a798a04e22a8aae8d9ba70fe29ec99ebd63261ac18d7c9a6131' 
  AND token = 'cEZ0+3rTu1QX+6sM5qE6+Jm7vHdDIUzQcfh06TDG9ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}