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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4bb476a5eb0de3be077b82eb4432df049ca4c3e55cf633593cf424157f5e19' 
  AND token = 'wOYcmuZZMU7kEwLH2uL8prj25VpgU5bonwHQRuNJ+d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}