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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9ff60a9e1ccd0ada0f360d1971353814657b187abb3cf89ab069abc1f0a392' 
  AND token = '6o3XiC2NKX9aFoI5xWDMMKfha6MCIyuJoZMG43EX1Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}