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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d3611fb05604007467202978d1a14145e13e2a927202c01bd21aab5777f9ac' 
  AND token = 'XMJjfDYhmLdOAMuwkyQgRtGGxbNyUmEztS7ga5CpF4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}