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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5617a8aeb0fa847285e2fc7c4c986fbbb691de12cc2dca3d7d7c7cb22e2be6ec' 
  AND token = '+DRc0dXSDW21MumT0tNnIUNx7I3R4hA0MNfUYYjVJDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}