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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d164de9d70e21479e3e991ceac7073446d8043ff92252a56ad31c9b6138df94' 
  AND token = 'bggQLVy/rlk6KKCVeQ+uCYWsKDIIMurMTKQGUMqdsWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}