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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3378bc251f6e37d5d2e816083d80f063b4e60592af4e35917959816eee2bb3e' 
  AND token = 'x7rpNWBhXQ6uMrwo1TaNKsgdhgjHnT0xsmx7M8Y0PDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}