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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b175d5c95ea7a7685d95f39ad16b61f084968d4f57cb1d402105e00bb9cd989' 
  AND token = 'RHwO2n9r3EC4FFvm6RcYJyYrTFKy38qc5gjOpLwIDS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}