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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e66dd4aca7c92fd34ebee5afdddc94578b39cfdc0d7746cd4b2394bcf71f31e' 
  AND token = 'OIsaqUOVnZBSrK0REgA7igT0vgVk3cw4mr+DRQ5y7ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}