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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4a33123e4409a876e0ca9bc0a5ef543e410e8880cde2553b274b4843d9c526a' 
  AND token = 'pB38/5T6Ku+InK2z2E4xNMMEQUbp0EBt/chg7XMluVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}