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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f41192be8795914b017ce806add127e27a0ccb15b89260e2f8512b67e3e9d27' 
  AND token = 'hmQ/T2WjJoWYSmScEMo5M57QvqWSoPhRbHK800R9hMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}