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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8d0a444cacf6b381770daffdae5d5c0201dac79d8b0460b6e732f87c2a9482' 
  AND token = '6s/CU6CekcGRn3dKmVqGtMkgVQtLnuzrDS6U5FUP+38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}