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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1727518f1dd803e2c8abb687f4cbe2d67d4f90a90095012a49d8adbed11d30' 
  AND token = '+cMn6HfHKCzEc9D20M/SCUNLEqpfKm4n4UOI8J5OJV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}