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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80ddc9150bde32f823b56e1109ef4904687a3878a243aae5a0eeec7dc3f2303' 
  AND token = '6nbvuHQWLFX3p9/m+FK7xeXw3BMOJayDspduVkBjFX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}