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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2013e0be216a55a4dfcb600d9af0b2d6c3ace5915d542b0e75bad5455b575043' 
  AND token = 'PZwT0+JqbbF9YOqSaFedCo/5wgdIjjL1H1T+nvveAMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}