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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b8a6ade52c96f413340c82a6aaad5e1ed26d647bfefe29855fc7ccabf1451f' 
  AND token = 'ol7nM7QSgQlsLLhMQghAkzFtUyT3js4P4ETK6LAXdbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}