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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92f8cd6b8955aacbe01c531a55a18b56d2035b020220bc84cb561bf86dd8f9e4' 
  AND token = 'm2eI6xlT/Ai9oxxgLyyZGM4b/+ToogwQcO6ymfWYnq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}