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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5405de9e111237efd0ef07cf1641801d01e8c4f639ae2e13968f9284a9cf1ef' 
  AND token = 'xkytQU+v6PuXdfEkIeYxEkDH8D0hsWfvnB8FY7NmrXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}