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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c01c50d5462c46cdd81b7c3f397ebe1aed6f18f12bb16698e18288de985280d4' 
  AND token = 'PGEdWfDTLHk7bpx0SJ2gtXGv7F2q9m+i6rMu6+TFjJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}