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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fcd69b46b6e3dd3a219e5ec659b8ec7cfac598476ad1f069360cc96f86123b' 
  AND token = 'EWpENIgCwSq4pCpT+939nSq2exFAgbG4wtxJWZs0xV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}