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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9f8b49ebd64f40e305c8316a9d7a91febe58c3b0e22825581aa9f5647e35cc3' 
  AND token = 'kHvFCDiGvp0YM1kiaw90MvamB0ESWhDVpSFtculh2XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}