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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0c49d1187a41914e72ad7e86e471e9765c2ab57033ebd0994a3837829552eb' 
  AND token = 'MvLF94jvtbwm3A9hfsRvNadhtYF5Wik4kvq9ycpnsZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}