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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581f8b26fbf26aa9aa0268fbdce8d0e4d1e16c326c4e56169c49f3fbef9d0bbe' 
  AND token = 'XW7Ch/Oa0yi1kEVJXLEWDSZmTHa9RI+c+MetMfPONKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}