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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c4d2747da96593f061daac1cc018d5405ce68519ef2b51a63cf05555aec2a3' 
  AND token = 'NQo6CxaWRtycW2rECz10/ih7NM7QxiQaCLg+dteJYbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}