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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5fe35972b88f0c011cf5f2846bbda049beeda4d857ed068811734c93cff1e78' 
  AND token = 'inUu0XHxMVksqO/DS++nCEckS4t7iZCR6u65+WHL1RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}