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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed616764496685df4b0fe8123b1835f59bd665ff2ac898841f5a90da5eec4e09' 
  AND token = 's1tDpjwnFbnm+6SBVkw/BOrP5pDMWewct2j8IFasIXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}