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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5608fb3ed6824bd765df0501ef9e12f04bc180bedb85d5bd60ecd65b56f952a4' 
  AND token = 'SLEa6I4L0FySWC7OLbrGlftd4dtUCK18ILWiiJ/CVdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}