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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5cab73fb7643e331bbe68f236edee01b83bb1a148ad4d9ecbd83b1e525da89' 
  AND token = 'dj7Hbh6S8oWCAIb9bxAL3L8AXlHT5YMIMaO8fjmJmcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}