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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afec3989dec00b5c3cda1b4b21bd4e5e17dbeb6c7a36fd6710d62204ea1a8507' 
  AND token = 'cM4Fw5qEMDfaBU5y0uKomsGu8R/+gHJ2h5neyVucJLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}