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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '904255a05ae34e1082eda319f1756e53ea02527e378c22a3d7d5c8ca966bd47f' 
  AND token = '1d8v5OzNgXYxc0vi0ThTHOsDpHLvl1OtvOdgkaKrF5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}