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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b210c3c05f0f884a84a7f0c9fea196f95855f2e9e3ac3fb00ff83f7eb806425' 
  AND token = 'e+Dfgz0ze3ZaYMlLF/SCfxPfDkBXRTBbHRUYVZMjvkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}