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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ffed1a355e75b48abf8895717f7f49dbde6a6183892ae726873dd25ed95bc1' 
  AND token = '9+HOsUVlMGpVw/lqR9Hez+m2lTeDfUi4QHAHyj6fu6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}