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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a9ad642973ac4eb83ebe78e19e1ca8046ec5e1012e7b5f0be4d3014e0ec777' 
  AND token = 'OaJgVfqpTPeCi+o3MXtIWEBL3apdyCjaj2ZHT/MtxvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}