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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78891c203572f425a90a28908e3c633539d917cfa8e6f3b0b32ebf18d45352da' 
  AND token = 'ixmI4zrWS6Bkc+ylihO6WYlxhwN4xtyni46pvVbAyIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}