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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ecdbd5c1f9fb6b305d15325eb3ff03449c414d46b21b32495d0b1584b83791f' 
  AND token = 'cP4SCDJxHJYuFdSf2mqawSWEYhSg/ub+BqZYTY8hTa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}