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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7d1643f6f389857d32e8f46a2da4bfffd24fef5ad0509bfe482899fb521499' 
  AND token = 'w1EQNgJ2c9Wv91P++IQ6Rk9I/1HdXh0L2zDmYyXmkHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}