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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6bf3ef1507b5484a2e6336d9b5d5342cd19a6c29b98d398c14b69c321750bc' 
  AND token = 'dRQJC5XhSxaFpGoCfuyrzbBAc42H3GlwsGgG6NRh/xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}