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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b32c970084f487b6b25b8e36d04d2c177133c5b7b6c502f553b052f6f4288f6' 
  AND token = 'NZpK0ZIprpCWpcYH1OURiUUO51uccx0kCJOyP1LqkWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}