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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2fd488c0f3ad33c51a952209d56b49a2eef9066da2a872385cfc63d3c1677fe' 
  AND token = 'yblx4l+2fy1SduSz/rXgmqRF/nj66GSQvm0IDgvrzc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}