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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389dc93526a703028ea15219332bb5544ef9edece10925960ad95b6b93a195b0' 
  AND token = 'FNgdZcJ68D5tDEaO+BDvDjB2rAA6se14vbNqEGvnfjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}