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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497b55aa6899a5fb48cbe8ad8a84a37e25b437b2c29ad6ff02cd4c64d4ec8fa4' 
  AND token = 'YKloZR3PHT70ZZjAU4106HcmHEJkwEu9QIGI8Mh+mOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}