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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1f8cd850906375a0ff56527c18abfd0d40d4f5de205c6cd62d015056dc8dd5' 
  AND token = 'R6VFFL9txGaW+kG9IS6a3e37Eafm3I/3W4SXgbdVnB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}