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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '771a2fe15f64d41cc5a4c5dcee340c116756415b971f9cd465447a11192ab125' 
  AND token = 'tBslA35u/djJ2MIlqfgE+Nt0ZnAmPLEsW41JjgmalRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}