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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1f6b55399a059d2be34ee657c00a9355dd6d218e39ca122f220509442b11d3' 
  AND token = '8Bz9giXFBazY5Sq2D1wxjXwN+CHCldmP7bAf15I8Qi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}