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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2781d5f8e019351c7b265ef5b16e1ecefd1b9c712a32f59c75954a7a037c2623' 
  AND token = 'dL67a6tYISDnJOFR239yMXyKIxQRPcx9FMjYqml+pVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}