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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95f8e710698db237a8b47bb31774e639d3d8c1ac0d4619faba50329dfb6632b0' 
  AND token = 'rQoxA28YvD7sSEDchK1rpo3YmLWK8MvN684iWlmTyP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}