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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65dbc0b254c3c7bc8078168e7e61fc030fe46b2a1f3de42e8cabd00f9f5628e' 
  AND token = 'QhyKXd4ASXeNB7Hkc5A2CcoPQrp0Pyj2mjTfkRmeWqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}